What is MG?

Myasthenia gravis (MG) is an autoimmune disease. With MG, the immune system targets the communication point between the nerve and muscle (called the "neuromuscular junction"). MG causes weakness in voluntary muscles; this weakness worsens with activity and improves with rest.

MG's primary symptoms fluctuate, vary in severity and occur in many combinations. Symptoms may include droopy eyelids(s); double or blurred vision; weak arms, hands, neck, face or legs; difficulty chewing, smiling, swallowing or talking; excessive fatigue; difficult breathing or shallow respirations.

The name myasthenia gravis comes from Greek and Latin words meaning "grave muscle weakness." This reflects the situation for patients with MG before the discovery of many of the current treatments. Today, with appropriate therapy, most people with MG can expect to live normal or nearly normal lives. Also, sustained clinical remissions, although rare (10-15% of cases), can happen at any time.

Reviewed by the MGF of Illinois Medical Advisory Board, September 2008.

Unless otherwise stated, the information provided here is of a general nature, composed by non-medical personnel. It is meant to be accurate and helpful advice for MG patients. It is not intended to be medical opinion, nor is it a substitute for personal professional medical care.